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Brain traces: Neurobiology's emerging insights into schizophrenia and its treatment

Molecular biologist Prof Brian Dean talks about how both post-mortem and live imaging investigations of brain biology are helping to identify new treatment targets for the multifaceted condition of schizophrenia.

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SHANE HUNTINGTON
I’m Dr Shane Huntington. Thanks for joining us. Our moment to moment picture of our surroundings is something we generally take for granted. Our visual and aural perceptions are mostly seamless. But what if somebody told you that some of the things, some of the people even you see and hear were fictional or if your perceived reality was not the same as everybody else's? There's a range of neurological discords that can challenge the certainty of our perceptions. Schizophrenia is one of those conditions. It weakens our ability to distinguish between what is real and what is delusion or hallucination. As with many conditions that affect the brain, schizophrenia is complex and requires innovative approaches to research. But how can we investigate a disorder with symptoms such as delusions or fictional perceptions and what are the most effective treatments for schizophrenia? Today on Up Close we are speaking to one of the leaders in schizophrenia research, molecular biologist Professor Brian Dean. Brian is a senior research fellow at the Mental Health Research Institute, part of the Florey Institute of Neuroscience and Mental Health and Professor of Psychiatry here at the University...

The full text of this article can be purchased from Informit.