Australasian Science: Australia's authority on science since 1938

The Origins of Pollen Allergens

The full text of this article can be purchased from Informit.

The first broad picture of the evolution and possible functions of pollen allergens may help medical research into the reduction or prevention of allergic diseases such as asthma and allergic rhinitis (hayfever).

“During the past four decades, allergic diseases have become a global health problem,” says project leader Prof Dabing Zhang, who leads The University of Adelaide and Shanghai Jiao Tong University Joint Laboratory for Plant Science and Breeding. “Studies have shown that more than 50% of patients with perennial allergic rhinitis are sensitised to pollen allergens, and the number of people affected by pollen allergy is on the increase worldwide.

“Unfortunately, pollen allergens are difficult to avoid because of the extremely small size and high prevalence of pollen. This is a serious health issue, but very little is known about their evolutionary history and why plants have evolved these allergens.”

Zhang’s study, published in Plant Physiology, undertook a genome-wide analysis of potential pollen allergens in two model plants, Arabidopsis thaliana (thale cress) and rice, and compared the results with 25 species of plants ranging from simple algae to complex flowering plants. The findings were used to develop a model explaining how plants produced and maintained pollen allergens.

“This genetic and evolutionary insight our work has...

The full text of this article can be purchased from Informit.