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Vitamin D Deficiency Link to Childhood Asthma

Children with vitamin D deficiency are more likely to develop asthma, according to a study that tracked vitamin D levels from birth to age 10 in Perth children at high risk for asthma and allergy.

The findings, published in the Journal of Allergy and Clinical Immunology, showed that repeated bouts of vitamin D deficiency in early childhood were linked to higher rates of asthma at aged 10, as well as allergy and eczema.

“We know vitamin D plays an important role in regulating the immune system and promoting healthy lung development,” said lead author Dr Elysia Hollams from the Telethon Kids Institute. “But while it has been suggested that inadequate vitamin D may be a factor contributing to the surge in asthma rates over recent decades, previous studies investigating the relationship have yielded conflicting results. There has been a lack of research looking at whether vitamin D deficiency is more detrimental at certain periods in childhood.

“Our study is the first to track vitamin D levels from birth to asthma onset, and it has shown a clear link between prolonged vitamin D deficiency in early childhood and the development of asthma. We’ve also shown for the first time that babies deficient in vitamin D have higher levels of potentially harmful bacteria in their upper airways, and are more susceptible to severe respiratory infections.

“Earlier research by our team and others around the world has identified the first 2 years of childhood as a critical period during which allergies and chest infections can combine to drive asthma development in susceptible children. Our new findings identify vitamin D deficiency as a co-factor that may promote this process.”

However, Hollams cautioned against rushing out and purchasing vitamin D supplements. “We still don’t know what the optimal level of vitamin D is for good lung health and immune function, and we don’t know if supplementation would address this issue, or if healthy sun exposure is what is required given that vitamin D is an indirect measure of recent sun exposure.”